发明名称 |
MUTANTS OF STREPTOCOCCAL TOXIN C AND METHODS OF USE |
摘要 |
This invention is directed to mutant SPE-C toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-C toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-C toxin. The mutant SPE-C toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-C toxin.
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申请公布号 |
CA2273824(A1) |
申请公布日期 |
1998.06.11 |
申请号 |
CA19972273824 |
申请日期 |
1997.12.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
GAHR, PAMALA J.;MITCHELL, DAVID T.;OHLENDORF, DOUGLAS;SCHLIEVERT, PATRICK M. |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/09;A61P31/04;A61P37/04;C07K14/315;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/31;(IPC1-7):C12N15/31 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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