发明名称 LLG POLYPEPTIDES OF THE TRIACYLGLYCEROL LIPASE FAMILY, AND COMPOSITIONS AND METHODS FOR THEIR USE IN ENZYMATIC HYDROLYSIS, AND PROTEIN AND GENE THERAPIES
摘要 Lipoprotein Lipase like polypeptides, nucleic acids encoding said polypeptides, antisense sequences, and antibodies to said polypeptides are disclosed. Also disclosed are methods for the preparation of said polypeptides in a recombinant system and for the use of said polypeptides to screen for agonists and or antagonists of said polypeptides. Also disclosed are methods and compositions for the treatment of disorders of lipid metabolism.
申请公布号 WO9824888(A2) 申请公布日期 1998.06.11
申请号 WO1997US22331 申请日期 1997.12.05
申请人 RHONE-POULENC RORER PHARMACEUTICALS INC.;JAYE, MICHAEL, C.;DOAN, KIM-ANH, THI;KRAWIEC, JOHN, A.;LYNCH, KEVIN, J.;AMIN, DILIP, V.;SOUTH, VICTORIA, J. 发明人 JAYE, MICHAEL, C.;DOAN, KIM-ANH, THI;KRAWIEC, JOHN, A.;LYNCH, KEVIN, J.;AMIN, DILIP, V.;SOUTH, VICTORIA, J.
分类号 A01K67/027;A61K38/00;A61K38/46;A61K39/395;A61K45/00;A61K48/00;A61P3/06;C07K16/40;C12N5/10;C12N9/00;C12N9/18;C12N9/20;C12N15/09;C12P21/08;C12R1/91;G01N33/15;G01N33/50 主分类号 A01K67/027
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