A compound is described. The compound is suitable for use as an inhibitor of oestrone sulphatase. The compound has formula (I); wherein A is a first group; B is an aryl ring structure having at least 4 carbon atoms in the ring and wherein the ring B is substituted in at least the 2 position and/or the 4 position with an atom or group other than H; X is a sulphamate group; wherein group A and ring B together are capable of mimicking the A and B rings of oestrone; and wherein group A is attached to at least one carbon atom in ring B.
申请公布号
WO9824802(A2)
申请公布日期
1998.06.11
申请号
WO1997GB03352
申请日期
1997.12.04
申请人
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICIN;REED, MICHAEL, JOHN;POTTER, BARRY, VICTOR, LLOYD