METHOD OF PREPARING IMMUNODEPRESSANT CYCLOSPORIN A AND A STRAIN TOLYPOCLADIUM SPECIES CBS 630 92 PRODUCING CYCLOSPORIN A

摘要

FIELD: microbiology. SUBSTANCE: method of preparing immunodepressant cyclosporin A is carried out by culturing a strain Tolypocladium species CBS 630.92 on nutrient medium under aerobic condition. Nutrient medium has molasses and soybean flour as carbon and nitrogen sources or sucrose and cotton seed flour, respectively. After culturing cyclosporin A is isolated and purified. EFFECT: improved method of preparing. 4 cl, 7 tbli