| 摘要 |
This invention describes a dermatologic external preparation having an excellent effect of remedying the chaps of the skin, and being capable of stabilizing the lamellar liquid crystal structure, which comprises a ceramide and/or a structual analog of a ceramide, and one or more sterol derivatives represented by the formulas (V) or (VI): <CHEM> wherein R<1> represents a residue remaining after removing the hydrogen atom from the hydroxyl group of a natural sterol having one hydroxyl group or a hydrogenation product thereof, R<8> represents -(CH2)n- (n is an integer of 2 to 10) or - CH = CH -, M represents a hydrogen atom, alkali metal, ammonium, alkanol ammonium having 2 to 9 C-atoms in total, alkylammonium or alkenylammonium having 1 to 22 C-atoms in total, pyridinium which may be substituted by an alkyl or alkenyl group having 1-18 C-atoms, or basic amino acid, and L represents an alkaline earth metal. |
