发明名称 |
NOVEL FILARIID NEMATODE CYSTEINE PROTEASE PROTEINS, NUCLEIC ACID MOLECULES AND USES THEREOF |
摘要 |
<p>The present invention provides for filariid nematode cysteine protease proteins; to filariid nematode cysteine protease nucleic acid molecules, in particular, Dirofilaria immitis L3 larval cysteine protease nucleic acid molecules and Onchocerca volvulus L3 larval cysteine protease nucleic acid molecules; to antibodies raised against such proteins, and to compounds that inhibit filariid nematode cysteine protease activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies and/or inhibitors. The present invention also includes therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitors, and the use of such compositions to protect an animal from disease caused by parasitic helminths.</p> |
申请公布号 |
EP0846165(A1) |
申请公布日期 |
1998.06.10 |
申请号 |
EP19960919309 |
申请日期 |
1996.06.07 |
申请人 |
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION;HESKA CORPORATION |
发明人 |
WISNEWSKI, NANCY;GRIEVE, ROBERT, B.;FRANK, GLENN, R.;TRIPP, CYNTHIA, ANN |
分类号 |
C12N15/09;A61K35/68;A61K38/00;A61K38/46;A61K38/55;A61K39/00;A61K39/395;A61K48/00;A61P33/00;C07K14/435;C07K16/18;C07K16/40;C12N7/00;C12N9/64;C12N15/57;C12Q1/37;G01N33/50;G01N33/53;G01N33/569;(IPC1-7):C12N9/64;C07K16/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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