发明名称 |
PYRIDINOLINE CROSSLINKS AS MARKERS OF PERIODONTAL AND PERI-IMPLANT DISEASE ACTIVITY |
摘要 |
A method of diagnosing severity of periodontal disease or peri-implant disease in a human patient, involving a) obtaining a sample of tissue or gingival crevicular or other fluid from the mouth of said patient, or a blood or urine sample from the patient, and b) measuring a pyridinoline crosslinked compound in the sample as a measure of severity of disease. |
申请公布号 |
EP0745221(A4) |
申请公布日期 |
1998.06.10 |
申请号 |
EP19950909234 |
申请日期 |
1995.01.13 |
申请人 |
INSTITUTE OF MOLECULAR BIOLOGY, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
GIANNOBILE, WILLIAM, V.;LYNCH, SAMUEL, E.;WILLIAMS, RAY C., |
分类号 |
G01N33/50;G01N33/483;G01N33/53;G01N33/68;(IPC1-7):G01N33/48;G01N33/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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