发明名称 ALKYLENEDIAMINE DERIVATIVE, AND ANTITUMOR AGENT/ ANTIMICROBIAL AGENT
摘要 PROBLEM TO BE SOLVED: To obtain the subject new compound useful as an antimicrobial agent/ antitumor agent against Halicobacter pylori. SOLUTION: This compound is shown by formula I [W is a group shown by formula II (R1 and R2 are each H, a lower alkoxy, alkenyloxy or halogen; R3 and R3 ' are each methyl, prenyl or geranyl; and X is O or S) or by formula III (R10 is a lower alkyl; and R11 is a halogen); R4 to R6 are each H or a lower alkyl; Y is CH2 , O or the like; and (n) is 1-6] or its salt, e.g. a compound shown by formula IV. The compound shown by formula I is obtained by a known amido bond-forming method, such as the mixed acid anhydride, acid chloride, DCC, CDI or azide method, from a carboxylic acid shown by the formula WCOOH and an amine shown by formula V.
申请公布号 JPH10152471(A) 申请公布日期 1998.06.09
申请号 JP19970012056 申请日期 1997.01.06
申请人 SHISEIDO CO LTD 发明人 NISHINO CHIKAO;SATO FUMITAKA;UETAKE TOMOHIRO;FUKUNISHI HIROTADA;KOJIMA MITSUHISA
分类号 C07D295/12;A61K31/445;A61K31/495;A61K31/505;A61K31/535;A61K31/5375;A61P1/04;A61P31/04;C07D211/14;C07D239/42;C07D277/20;C07D277/38;C07D277/82;C07D295/13;C07D317/58 主分类号 C07D295/12
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