发明名称 |
Method for enhancing outflow of aqueous humor in treatment of glaucoma |
摘要 |
Elevated intra-ocular pressure is reduced by administration directly to the eye of benzmetanide that inhibits function of a Na+-K+-2Cl-2 cotransporter mechanism discovered in trabecular meshwork cells of mammalian eyes. Benzmetanide is useful in treatment of diseases of the eye associated with elevated intra-ocular pressure, such as ocular hypertension and glaucoma.
|
申请公布号 |
US5763491(A) |
申请公布日期 |
1998.06.09 |
申请号 |
US19950568389 |
申请日期 |
1995.12.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
BRANDT, JAMES D.;O'DONNELL, MARTHA E.;CURRY, FITZ-ROY E. |
分类号 |
A61K31/00;A61K31/196;A61K31/341;A61K31/402;A61K31/44;(IPC1-7):A61K31/18 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|