发明名称 |
Further improvements relating to radiolabelling of proteins |
摘要 |
PCT No. PCT/GB92/02322 Sec. 371 Date Jun. 16, 1994 Sec. 102(e) Date Jun. 16, 1994 PCT Filed Dec. 15, 1992 PCT Pub. No. WO93/11796 PCT Pub. Date Jun. 24, 1993A structurally modified protein is provided that will bind to a tumor-associated structure wherein the amino group in at least one basic amino acid in the binding protein is structurally modified to convert the amino group, -NH2, to the grouping -NH-CO-X-NHR in which R is H or an amino protecting group and the grouping -CO-X-NHR is the residue of a peptide of the formula NHR-X-COOH capable of acting as a substrate for a phosphokinase.
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申请公布号 |
US5762906(A) |
申请公布日期 |
1998.06.09 |
申请号 |
US19940244855 |
申请日期 |
1994.06.16 |
申请人 |
BRITISH TECHNOLOGY GROUP LTD. |
发明人 |
CREIGHTON, ANDREW MALCOLM |
分类号 |
G01N33/53;A61K47/48;A61K51/00;A61K51/08;C07K1/107;C07K1/113;C07K1/13;C07K7/06;C07K16/00;C07K17/02;C07K19/00;G01N33/534;G01N33/574;(IPC1-7):A61K51/00;A61M36/14 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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