| 摘要 |
<p>A phosphodiesterase IV inhibiting cathecol derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, in which R1 is C1-7 alkyl; C3-7 cycloalkane; phenyl optionally substituted with lower alkyl, lower alkoxy, nitro or halogen; pyrimidine optionally substituted with lower alkyl, lower alkoxy, nitro or halogen; or pyridine optionally substituted with lower alkyl, lower alkoxy, nitro or halogen; X, Y and Z are each independently oxygen, nitrogen or sulfur optionally substituted with C1-7 alkyl, C3-7 cycloalkane or phenyl; W is oxygen or sulfur is disclosed. In addition, a process for producing the compound of general formula (I) and a pharmaceutical composition containing pharmaceutically effective amount of the compound of general formula (I) are disclosed.</p> |
