| 摘要 |
<p>Novel phenanethridinium derivatives represented by general formula (A): wherein R1 represents a substituted or unsubstituted lower aliphatic hydrocarbon; R represents an aliphatic hydrocarbon chain bearing 2 to 6 carbon atoms and optionally having a substituent selected among lower alkyl groups, halogen atoms, and a hydroxyl group; Y and Z represent each a hydrogen atom, a hydroxyl group, or a lower alkoxy group or alternatively Y and Z combine with each other to form a methylenediocy group or a benzene ring; X- represents an acid residue or a hydroacid residue, having antitumor activites and the resistances to chemical reduction and biological metabolism, thus being advantageously used as a pharmaceutical.</p> |
