| 摘要 |
PURPOSE:To provide a vascularization inhibitor having a remarkable vasculrization-inhibiting activity and useful for preventing or treating diseases caused by the abnormal multiplication of blood vessels by containing WF2015A and/or WF2015B as active ingredients. CONSTITUTION:A vascularization inhibitor having the above-mentioned activity and useful for preventing or treating diabetic retinopathy, rheumatic arthritis, immature infant retinopathy, senile macular degeneration, etc., contains WF2015A (X = formula II) and/or WF2015B (X = formula III) represented by formula I (X is formula II or III) as active ingredients. The active ingredients can be mixed with a carrier acceptable as a drug and orally or parenterally administered in a form of capsules, tablets, granules, powders, oral tablets, sublingual tablets, solutions, etc., preferably in a does of usually 0.01-10mg/kg/ day in the case of injection and 0.5-50mg/kg/day in the case of oral administration. |
