METHOD FOR DIFFERENTIATING OR DETECTING PARTICLES IN A SAMPLE BY IDENTIFYING SIGNAL SEGMENTS OF TIME-RESOLVED, OPTICAL RAW SIGNALS FROM THE SAMPLE ON THE BASIS OF SINGLE PHOTON DETECTION

摘要

Method for differentiating or detecting particles in a sample, in which several particle types can be found, by identifying signal segments of time-resolved, optical raw signals from the sample on the basis of single photon detection (single pulse detection), wherein the sample contains at least two types of particles; the sample is illuminated by a light source; the optical raw signals emanating from the sample and arising from at least one measuring volume element (V), wherein V 1, are detected by at least one detection unit; at least one particle generates a signal component during its stay in the measuring volume element; a signal segment of the optical raw signals is determined by active and/or passive entrance and re-exit of the particle into or out of the measuring volume element; the optical raw signals are broken down into any number of segments; at least one statistic based on the optical raw signals is drawn up for at least any given segment, and at least one statistic or at least one combination of several statistics are evaluated according to the availability of characteristics which typify the signal component of at least one particle type.