摘要 |
The invention refers to a process for the production of the form I of the terazosin monohydrochloride anhydrous by treating at the boiling temperature terazosin monohydrochloride dihydrate with a mixture made by methanol and by a solvent selected from the alcohols, straight or branched, from C2 to C6, the esters of the carboxylic aliphatic acids from C1 to C8 with the alcohols, straight or branched, from C1 to C8, the aliphatic ketones from C3 to C8, the aliphatic ethers, straight, branched or cyclic, from C4 to C8, the aliphatic amides and the aliphatic nitriles. |