THE PRODUCTIVE MICROORGANISM STREPTOMYCES AUREOFACIENS PRODUCING CHLOROTETRACYCLINE IN A LONG-TERM CULTIVATION AND THE METHOD OF ITS CULTIVATION

摘要

Productive strain of Streptomyces aureofaciens CCM 4447 microorganism producing chlorotetracycline in a long-term cultivation is described. Initial concentration of phosphate is modified, in dependence on duration of cultivation, and ranges from 100 to 120 mg.lexp(-1) and with reduced level of ammoniac nitrogen from 0,4 to 0,6 g.lexp(-1) in cultivating medium.