发明名称 |
Bone resorption inhibition/osteogenesis promotion compound |
摘要 |
PCT No. PCT/JP94/00489 Sec. 371 Date Mar. 1, 1995 Sec. 102(e) Date Mar. 1, 1995 PCT Filed Mar. 25, 1994 PCT Pub. No. WO94/21667 PCT Pub. Date Sep. 29, 1994A compound represented by the following formula (I):X-Y-Z(I)[where Y is represented by the following formula (III): <IMAGE> (III) <IMAGE> (IV) <IMAGE> (V) X is a monovalent group of a tetracycline type compound, and Z is a monovalent group of a steroid type compound such as estrogen]. The compound can concentrate on the bone tissue and has a bone resorption inhibition/ossification promotion functions.
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申请公布号 |
US5760214(A) |
申请公布日期 |
1998.06.02 |
申请号 |
US19950338505 |
申请日期 |
1995.03.01 |
申请人 |
ISKRA INDUSTRY CO., LTD.;INSTITUTE OF PHARMACOLOGY, WEST CHINA UNIV. OF MEDICAL SCIENCES |
发明人 |
ZHENG, HU;WENG, LINGLING |
分类号 |
A61K31/56;A61K31/565;A61K31/566;A61K31/57;A61K31/575;A61K31/58;A61K31/65;A61P3/02;A61P19/08;A61P19/10;A61P43/00;C07J41/00;C07J43/00;C07J71/00;(IPC1-7):C07D295/04 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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