发明名称 Bone resorption inhibition/osteogenesis promotion compound
摘要 PCT No. PCT/JP94/00489 Sec. 371 Date Mar. 1, 1995 Sec. 102(e) Date Mar. 1, 1995 PCT Filed Mar. 25, 1994 PCT Pub. No. WO94/21667 PCT Pub. Date Sep. 29, 1994A compound represented by the following formula (I):X-Y-Z(I)[where Y is represented by the following formula (III): <IMAGE> (III) <IMAGE> (IV) <IMAGE> (V) X is a monovalent group of a tetracycline type compound, and Z is a monovalent group of a steroid type compound such as estrogen]. The compound can concentrate on the bone tissue and has a bone resorption inhibition/ossification promotion functions.
申请公布号 US5760214(A) 申请公布日期 1998.06.02
申请号 US19950338505 申请日期 1995.03.01
申请人 ISKRA INDUSTRY CO., LTD.;INSTITUTE OF PHARMACOLOGY, WEST CHINA UNIV. OF MEDICAL SCIENCES 发明人 ZHENG, HU;WENG, LINGLING
分类号 A61K31/56;A61K31/565;A61K31/566;A61K31/57;A61K31/575;A61K31/58;A61K31/65;A61P3/02;A61P19/08;A61P19/10;A61P43/00;C07J41/00;C07J43/00;C07J71/00;(IPC1-7):C07D295/04 主分类号 A61K31/56
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