| 摘要 |
PCT No. PCT/US95/06473 Sec. 371 Date Mar. 22, 1996 Sec. 102(e) Date Mar. 22, 1996 PCT Filed May 23, 1995 PCT Pub. No. WO95/31980 PCT Pub. Date Nov. 30, 1995A method is provided to treat and/or prevent striae distensae lesions by topically applying to the skin affected with the lesions an effective amount of a treatment composition containing an alpha hydroxy acid, such as glycolic acid, preferably by daily application in a pharmaceutically acceptable vehicle, such as a cream base, at a concentration of from 2 to 30 percent by weight. When applied during the striae rubrae stage, the alpha hydroxy acid may be effective to prevent the formation of striae albae lesions, and when applied in either stage, the alpha hydroxy acid may be effective to reduce the width and depth of the lesions, and improve the color of striae rubrae.
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