| 发明名称 |
FUSION PROTEINS WITH A EUKARYOTIC BALLAST PORTION |
| 摘要 |
A suitable "ballast portion" for fusion proteins is part of the amino acid sequence of interleukin-2 (IL-2) which contains significantly fewer than 100 amino acids. It is advantageous to start from a synthetic IL-2 gene which is divided by unique cleavage sites into six segments, up to three of which can be linked in arbitrary sequence by the modular principle. The invention permits specific constructions with which the solubility of the fusion protein can be altered.
|
| 申请公布号 |
CA1339894(C) |
申请公布日期 |
1998.06.02 |
| 申请号 |
CA19860525858 |
申请日期 |
1986.12.19 |
| 申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
HABERMANN, PAUL |
| 分类号 |
C12N15/09;A61K35/74;A61K38/00;A61P37/00;C07H21/04;C07K14/00;C07K14/52;C07K14/535;C07K14/54;C07K14/55;C07K14/62;C07K14/815;C07K19/00;C12N1/20;C12N1/21;C12N15/00;C12N15/26;C12P21/02;C12R1/19;C12R1/645;(IPC1-7):C12N15/62;C12N15/15;C12N15/17 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
