| 发明名称 |
Synthesis of hydroxysulfone and related compounds |
| 摘要 |
This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.
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| 申请公布号 |
US5760249(A) |
申请公布日期 |
1998.06.02 |
| 申请号 |
US19960704195 |
申请日期 |
1996.08.28 |
| 申请人 |
MERCK & CO., INC.;ZENECA LIMITED |
发明人 |
MATHRE, DAVID J.;SOHAR, PAUL;MOODY, DAVID;BLACKER, ANDREW J. |
| 分类号 |
C07D495/04;(IPC1-7):C07D495/04 |
主分类号 |
C07D495/04 |
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