发明名称 |
Methods of treating disease using sertoli cells and allografts or xenografts |
摘要 |
The present invention describes a method of treating a disease that results from a deficiency of a biological factor which comprises administering to a mammal Sertoli cells and cells that produce the biological factor. In particular, the present invention describes a method of treating diabetes mellitus by transplanting pancreatic islet of Langerhans cells in conjunction with Sertoli cells to create an immunologically privileged site. A method of creating an immunologically privileged site in a mammal for cellular transplants is further described by the present invention. A pharmaceutical composition comprising Sertoli cells and cells that produce a biological factor is also provided.
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申请公布号 |
US5759534(A) |
申请公布日期 |
1998.06.02 |
申请号 |
US19950467338 |
申请日期 |
1995.06.06 |
申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
SELAWRY, HELENA P. |
分类号 |
A61K38/28;A61K35/12;A61K35/39;A61K35/407;A61K35/48;A61K38/00;A61K38/13;A61K48/00;A61P3/08;A61P3/10;C12N5/071;(IPC1-7):A01N63/00;A01N65/00 |
主分类号 |
A61K38/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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