| 摘要 |
PROBLEM TO BE SOLVED: To obtain an electrode comprising a substrate, a conductor disposed on the substrate, an insulator coated on the conductor, while securing a connection region on the surface of the conductor to an outer member, the opening of the insulator, and a nucleic acid immobilized on the exposed conductor, and useful for a sensor capable of detecting a nucleic acid. SOLUTION: This electrode 10 useful for a sensor for detecting a target nucleic acid, etc., comprises a substrate 12, a conductor 11 disposed on the substrate 12, an insulator 14 coated on the surface of the conductor 11, while securing a connection region to an outer member, an opening 13 disposed in the insulator so as to partially expose the conductor 11, and the first nucleic acid immobilized on the conductor 11 exposed in the opening 13. The detection of the target nucleic acid is carried out by hybridizing the first nucleic acid immobilized on the electrode 10 with the second complementary nucleic acid on the electrode in preset conditions, applying a voltage to the first nucleic acid immobilized on the electrode and subsequently measuring the signal generated by the application. |
