7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same

摘要

A method is provided for preparing intermediates for 7-oxabicycloheptane carboxylic acid intermediates of the structures <IMAGE> <IMAGE> wherein R is alkyl, aryl, arylalkyl or cycloalkyl; R1 is alkyl, arylalkyl or cycloalkyl; R2 is aryl or arylalkyl; and of the structure <IMAGE> where R and R1 are as defined above, which may be used in making the final anti-thrombotic-anti-vasospastic compounds.