发明名称 NOVEL HETEROCYCLIC COMPOUNDS.
摘要 <p>A compound of formula (I), wherein R1 and R2 independently are hydrogen, halogen, trifluoromethyl, hydroxy, C1-6-alkyl or C1-6-alkoxy; and R3 is hydrogen or C1-3-alkyl; and A is C1-3-alkylene; and Y is ><u>C</u>H-CH2-,><u>C</u>=CH-, ><u>C</u>H-O-, ><u>C</u>=N-,><u>N</u>-CH2- wherein only the underscored atom participates in the ring system, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.</p>
申请公布号 MX9802126(A) 申请公布日期 1998.05.31
申请号 MX19980002126 申请日期 1996.09.12
申请人 NOVO NORDISK A/S. 发明人 ROLF HOHLWEG;TINE KROGH JORGENSEN;KNUD ERIK ANDERSEN;UFFE BANG OLSEN;PETER MADSEN;ZENDEK POLIVKA;OTYLIE KONIGOVA;FRANTISEK MIKSIK;MARTINA KOVANDOVA
分类号 C07D321/12;A61K31/335;A61K31/357;A61K31/4406;A61K31/55;A61P3/08;A61P25/00;A61P29/00;C07D273/00;C07D273/01;C07D405/06;C07D405/12;C07D413/06;(IPC1-7):C07D405/06;A61K31/40;A61K31/445;A61K31/455 主分类号 C07D321/12
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