发明名称 N-(ARYL/HETEROARYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS
摘要 Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 WO9822441(A2) 申请公布日期 1998.05.28
申请号 WO1997US20356 申请日期 1997.11.20
申请人 ATHENA NEUROSCIENCES, INC.;ELI LILLY & COMPANY;AUDIA, JAMES, E.;FOLMER, BEVERLY, K.;JOHN, VARGHESE;LATIMER, LEE, H.;NISSEN, JEFFREY, S.;REEL, JON, K.;THORSETT, EUGENE, D.;WHITESITT, CELIA, A. 发明人 AUDIA, JAMES, E.;FOLMER, BEVERLY, K.;JOHN, VARGHESE;LATIMER, LEE, H.;NISSEN, JEFFREY, S.;REEL, JON, K.;THORSETT, EUGENE, D.;WHITESITT, CELIA, A.
分类号 C07D317/24;A61K31/223;A61K31/27;A61K31/341;A61K31/357;A61K31/36;A61K31/40;A61K31/404;A61K31/428;A61P25/28;C07C229/18;C07C229/60;C07C247/16;C07C255/58;C07C259/14;C07C259/16;C07C259/18;C07D207/325;C07D209/08;C07D215/38;C07D229/02;C07D277/62;C07D307/12;C07D317/58;C07D319/06;C07D319/18;C07K14/47 主分类号 C07D317/24
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