发明名称 N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING beta -AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
摘要 Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 WO9822493(A2) 申请公布日期 1998.05.28
申请号 WO1997US18704 申请日期 1997.11.20
申请人 ATHENA NEUROSCIENCES, INC.;ELI LILLY & COMPANY;AUDIA, JAMES, E.;FOLMER, BEVERLY, K.;JOHN, VARGHESE;LATIMER, LEE, H.;NISSEN, JEFFREY, S.;PORTER, WARREN, J.;THORSETT, EUGENE, D.;WU, JING 发明人 AUDIA, JAMES, E.;FOLMER, BEVERLY, K.;JOHN, VARGHESE;LATIMER, LEE, H.;NISSEN, JEFFREY, S.;PORTER, WARREN, J.;THORSETT, EUGENE, D.;WU, JING
分类号 A61K38/00;A61P25/28;A61P43/00;C07K5/06;C07K5/065 主分类号 A61K38/00
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