C1q RECEPTOR, ENCODING GENE AND APPLICATION IN HOST DEFENSE ENHANCEMENT

摘要

Nucleic and amino acid sequences for a cell surface transmembrane glycoprotein designated C1qRp are taught. A method by which the nucleic acid sequence encoding C1qRp may be used to modulate the role of the immune system is also described. Transgenic animals created with heterologous DNA sequence encoding C1qRp are described as well as antibodies directed against the C1qRp protein. A method of hybridization for C1qRp nucleic acid using oligonucleotide probes based on the C1qRp nucleic acid sequence and methods for detecting a hybrid probe: target C1qRp duplex are also taught including a kit for such detection.