发明名称 MULTIVALENT SALTS OF PYRIDOSTIGMINE AND RELATED COMPOUNDS
摘要 A quaternary ammonium cholinergic agent is complexed with a multivalent anion, or with multiple monovalent anions. The complex may be administered orally to a patient to treat pain, or for some other purpose. Numerous modifications are contemplated, including modifications to the ring structure of the compound, substitution and functionalization of the ring. Other contemplated modifications include the use of different anions, including various monovalent and polyvalent anions, and both organic and inorganic anions. The compounds have utility as cholinergic agents, and especially in the treatment of mysasthenia gravis, chest pain, and carpal tunnel syndrome.
申请公布号 WO9822458(A1) 申请公布日期 1998.05.28
申请号 WO1997US20509 申请日期 1997.11.10
申请人 ICN PHARMACEUTICALS, INC.;GRANGER, COLIN, D.;ORR, ROBERT;RAMASAMY, KANDASAMY 发明人 GRANGER, COLIN, D.;ORR, ROBERT;RAMASAMY, KANDASAMY
分类号 C07D213/64;A61K31/27;A61K31/44;A61P21/04;A61P43/00;C07C271/42;C07C271/52;C07D213/65;C07D239/34;(IPC1-7):C07D401/06;C07D401/08;C07D401/10;C07D401/12;C07D407/06;C07D407/08;C07D407/10;C07D407/12;C07C271/56;C07C271/58;A61K31/435;A61K31/35;A61K31/40;A61K31/33 主分类号 C07D213/64
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