| 摘要 |
PCT No. PCT/SE95/00761 Sec. 371 Date Jul. 10, 1995 Sec. 102(e) Date Jul. 10, 1995 PCT Filed Jun. 21, 1995 PCT Pub. No. WO96/16082 PCT Pub. Date May 30, 1996The present invention relates to variants of Penicillin Binding Proteins (PBP), which proteins are involved in bacterial peptidoglycan biosynthesis. Disclosed are also DNA molecules coding for the said PBP variants, as well as vectors and cells harbouring such DNA molecules. The invention is also related to processes for assaying and designing therapeutically useful compounds which have high affinity to PBP, which processes utilize the said PBP variants. |
