发明名称 SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS
摘要 <p>Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have generalized formula (I) in which T is a pharmaceutically acceptable substituent group; A is CH2, CH, or N; G is CH2 or CH; and R1 is any of a variety of disclosed substituent groups. The class of compounds of the invention includes ring-containing materials in which the units A and G are joined. The compounds of the invention are mixtures of diastereomers, or individual diastereomers making up these mixtures.</p>
申请公布号 WO1998022436(A1) 申请公布日期 1998.05.28
申请号 US1997019960 申请日期 1997.10.30
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