发明名称 METHODS AND COMPOUNDS FOR INHIBITING beta -AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS
摘要 Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 WO9822494(A2) 申请公布日期 1998.05.28
申请号 WO1997US20804 申请日期 1997.11.21
申请人 ATHENA NEUROSCIENCES, INC.;ELI LILLY & COMPANY;AUDIA, JAMES, E.;BRITTON, THOMAS, C.;DROSTE, JAMES, J.;FOLMER, BEVERLY, K.;HUFFMAN, GEORGE, W.;JOHN, VARGHESE;LATIMER, LEE, H.;MABRY, THOMAS, E.;NISSEN, JEFFREY, S.;PORTER, WARREN, J.;REEL, JON, K.;THORSETT, EUGENE, D.;TUNG, JAY, S.;WU, JING;EID, CLARK, NORMAN;SCOTT, WILLIAM, LEONARD 发明人 AUDIA, JAMES, E.;BRITTON, THOMAS, C.;DROSTE, JAMES, J.;FOLMER, BEVERLY, K.;HUFFMAN, GEORGE, W.;JOHN, VARGHESE;LATIMER, LEE, H.;MABRY, THOMAS, E.;NISSEN, JEFFREY, S.;PORTER, WARREN, J.;REEL, JON, K.;THORSETT, EUGENE, D.;TUNG, JAY, S.;WU, JING;EID, CLARK, NORMAN;SCOTT, WILLIAM, LEONARD
分类号 A61K38/00;A61K31/165;A61K31/216;A61K38/55;A61P25/28;C07C237/22;C07K5/06;C07K5/062;C07K5/065;C07K5/08;C07K5/083;C07K5/087 主分类号 A61K38/00
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