hRAD54

摘要

hRAD54 polypeptides and DNA (RNA) encoding such enzyme and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such hRAD54 in the development of treatments for cancer prone syndromes, such as Xeroderma Pigmentosum and Bloom syndrome, Wemer's syndromes, and X-linked Mental Retardation with alpha-thalassemia Syndrome (ATR-X); as well as cancers, such as that of the breast, among others, are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides.