Asymmetric hydrogenation of dihyrofuroimidazole derivatives

摘要

A process for the asymmetric hydrogenation of the furoimidazole derivatives of the general formula: hich is cleavable in a known way, and R2 is hydrogen or a protective group, which is cleavable in a known way, with hydrogen in the presence of a homogeneous catalyst to the corresponding diastereomeric tetrahydrofuroimidazole derivatives of the general formula: <IMAGE> II The tetrahydrofuroimidazole derivatives of the general formula II are intermediate products for the production of vitamin (+) biotin./!