METHOD FOR INCREASING THE SOLUBILITY OF CLEMASTINE AND PHARMACEUTICAL COMPOSITIONS PREPARED THEREFROM
摘要
A method is disclosed for increasing the solubility of clemastine through the use of organic acid or its salts as a solubilizing agent. Particularly useful as solubilizing agents are salts of carboxylic acids, such as fumarate, maleate and citrate. Pharmaceutical compositions containing clemastine, and organic acids or its salts as solubilizing agents, are also disclosed.