发明名称 |
PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS |
摘要 |
An anti-Pseudomonas aeruginosa agent which is substantially pure biologically active colistin component, a mixture thereof or a pharmaceutically acceptable salt thereof delivered as an aerosol or dry powder formulation. The figure shows a general structure of a prodrug colimycin (Figure 1A) and a generic formula of a drug colistin and its components substituents (Figure 1B). A formulation and method for preparation of substantially pure biologically active colistin component, a mixture thereof or a pharmaceutically acceptable salt thereof. A method for treatment and prophylaxis of Pseudomonas aeruginosa, Stenotrophomonas maltophilia or other susceptible pulmonary bacterial infections.
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申请公布号 |
CA2242335(A1) |
申请公布日期 |
1998.05.22 |
申请号 |
CA19972242335 |
申请日期 |
1997.11.13 |
申请人 |
PATHOGENESIS CORPORATION |
发明人 |
VANDEVANTER, DONALD R.;MONTGOMERY, ALAN B. |
分类号 |
A61K9/12;A61K9/00;A61K38/00;A61K38/12;A61P11/00;A61P31/04;C07K7/50;C07K7/62;(IPC1-7):C07K7/60 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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