Complementary DNA and genomic clones for three variants of GST- pi are disclosed. It is demonstrated that certain of these variants are overexpressed in gliomas, thereby indicating an involvement with that form of cancer. This permits the detection and treatment of certain classes of tumors using new compositions such as GST- pi genes, oligonucleotides, peptides and antibodies.
申请公布号
WO9821359(A1)
申请公布日期
1998.05.22
申请号
WO1997US20987
申请日期
1997.11.12
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;THE UNIVERSITY OF MISSISSIPPI
