发明名称 |
Methods of treating or preventing cardiac arrhythmia |
摘要 |
This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium in a use-dependent and/or rate dependent manner, and which provide the selective block preferentially at fast heart rates so that the effect is realized or maximized when required. |
申请公布号 |
AU5154898(A) |
申请公布日期 |
1998.05.22 |
申请号 |
AU19980051548 |
申请日期 |
1997.10.29 |
申请人 |
MERCK & CO., INC. |
发明人 |
JOSEPH J. LYNCH JR.;JOSEPH J SALATA;RICHARD J. SWANSON;BERNARD FERMINI |
分类号 |
C07D237/24;A61K31/00;A61K31/50;A61K31/66;A61K45/00;A61P9/00;A61P9/06;A61P43/00;C07F9/53 |
主分类号 |
C07D237/24 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|