发明名称 Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
摘要 A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method comprises the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention also provides a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent.
申请公布号 AU5425498(A) 申请公布日期 1998.05.22
申请号 AU19980054254 申请日期 1997.10.27
申请人 PHOTOGEN, INC. 发明人 ERIC A. WACHTER;WALTER G. FISHER;H. CRAIG DEES
分类号 G01N21/64;A61B17/00;A61B19/00;A61K41/00;A61K49/00 主分类号 G01N21/64
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