| 发明名称 |
Staphylococcus FabD (malonylCoA:ACP transacylase) protein |
| 摘要 |
<p>FabD polypeptides and DNA (RNA) encoding such FabD and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such FabD for the treatment of infection, particularly bacterial infections. Antagonists against such FabD and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of FabD nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding Fab (Fatty acid biosynthesis) and for detecting the polypeptide in a host.</p> |
| 申请公布号 |
EP0843016(A2) |
申请公布日期 |
1998.05.20 |
| 申请号 |
EP19970303530 |
申请日期 |
1997.05.23 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
GENTRY, DANIEL ROBERT;LONSDALE, JOHN TIMOTHY;PAYNE, DAVID JOHN;PEARSON, STEWART C. |
| 分类号 |
G01N33/50;A61K38/00;A61K38/45;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61P1/00;A61P9/00;A61P11/00;A61P11/02;A61P13/00;A61P13/02;A61P15/00;A61P17/00;A61P19/02;A61P19/08;A61P25/00;A61P27/02;A61P27/16;A61P31/04;A61P43/00;C07K14/31;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/10;C12N15/00;C12N15/09;C12N15/54;C12P21/02;C12P21/08;C12Q1/68;C12R1/445;G01N33/15;G01N33/53;G01N33/563;(IPC1-7):C12N15/54;C12Q1/48;G01N33/68;C07K16/40 |
主分类号 |
G01N33/50 |
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