发明名称 |
RsbU-1 derived from Staphylococcus |
摘要 |
<p>isbU-I polypeptides and DNA (RNA) encoding such rsbU-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such rsbU-1 forlm the treament of infection, particularly bacterial infections. Antagonists against such rsbU-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assay for detecting diseases related to the presence of rsbU-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.</p> |
申请公布号 |
EP0843011(A2) |
申请公布日期 |
1998.05.20 |
申请号 |
EP19970308512 |
申请日期 |
1997.10.24 |
申请人 |
SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM PLC |
发明人 |
FOSBERRY, ANDREW P.;LAWLOR, ELIZABETH J.;NICHOLAS, RICHARD O. |
分类号 |
G01N33/53;A61K38/00;A61K39/085;A61K39/395;A61K48/00;A61P1/00;A61P11/00;A61P13/02;A61P15/00;A61P25/00;A61P27/02;A61P29/00;A61P31/04;C07K2/00;C07K14/31;C12N15/09;C12N15/31;C12Q1/68;(IPC1-7):C12N15/31;A61K31/70;C07H21/00;G01N33/50;C07K16/12 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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