发明名称 NEUES CHELATISIERUNGSMITTEL, KOMPLEXVERBINDUNGEN, DIE AUS DIESEM MITTEL UND METALLATOMEN AUFGEBAUT SIND, UND DIAGNOSTISCHE MITTEL, DIE DIESE VERBINDUNGEN ENTHALTEN
摘要 A compound represented by general formula (I), a complex compound composed of the above compound and a metallic atom, and a diagnostic agent containing the complex compound, wherein m represents an integer of 1 to 3, R1 and R2 may be the same or different from each other and each represents hydrogen or lower alkyl, and R3, R4, R5 and R6 may be the same or different from one another and each represents hydroxy or (II), wherein n represents 0 or 1, X represents - NH- or -O-, Y represents alkylene, A represents hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl, and B represents alkyl or alkenyl, provided that two or three of the groups R3, R4, R5 and R6 are hydroxy and that when two of them are hydroxy groups, then the cases where R3 and R5 are hydroxy and where R4 and R6 are hydroxy are excluded. The first-mentioned compound is useful as a chelating agent and the complex compound has excellent characteristics as a contrast medium for diagnostic imaging. <CHEM>
申请公布号 DE69314613(T2) 申请公布日期 1998.05.14
申请号 DE1993614613T 申请日期 1993.03.22
申请人 THE GREEN CROSS CORP., OSAKA, JP 发明人 MORI, FUMIO, THE GREEN CROSS CORPORATION CENTRAL, HIRAKATA-SHI, OSAKA 573, JP;OKANO, TADASHI, THE GREEN CROSS CORPORATIO, HIRAKATA-SHI, OSAKA 573, JP;MURAKAMI, KAZUKI, THE GREEN CROSS CORPORATION, HIRAKATA-SHI, OSAKA 573, JP;SHINTOME, MASAKAZU, THE GREEN CROSS CORPORATION, HIRAKATA-SHI, OSAKA 573, JP;MUKAI, HIROMICHI, THE GREEN CROSS CORPORATION, HIRAKATA-SHI, OSAKA 573, JP;MIYAGI, IKUKO, THE GREEN CROSS CORPORATION, HIRAKATA-SHI, OSAKA 573, JP;IMAGAWA, TAKASHI, THE GREEN CROSS CORPORATIO, HIRAKATA-SHI, OSAKA 573, JP;KINDAICHI, SHOGEN, SUITA-SHI, OSAKA 565, JP;MARUKAWA, TARO, NAGOYA-SHI, AICHI 466, JP;KOZUKA, TAKAHIRO, KOBE-SHI, HYOGO 654, JP
分类号 A61K49/06;C07C229/16;C07C237/04;(IPC1-7):C07C229/06;A61K49/00 主分类号 A61K49/06
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