发明名称 |
ASSAYS USING REFERENCE MICROPARTICLES |
摘要 |
Disclosed is an assay for determining the presence of at least one analyte in a sample, which involves the steps of: (a) mixing the sample and predetermined amounts of first test microparticles having disposed thereon a binding molecule which binds a first analyte, and inert reference microparticles to form a reaction mixture, and to allow for the first binding molecule to bind the first analyte; (b) counting the numbers of the non-reacted first test microparticles and the reference microparticles; and (c) comparing the number of non-reacted first test microparticles to the reference microparticles to thereby establish a first test value so that the presence of the first analyte in the sample may be determined. In a preferred embodiment, the first test value is compared to a control value for a non-reactive sample, and a change value is calculated therefrom. Also disclosed are compositions and kits containing the microparticles.
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申请公布号 |
CA2240293(A1) |
申请公布日期 |
1998.05.14 |
申请号 |
CA19972240293 |
申请日期 |
1997.11.03 |
申请人 |
SIENNA BIOTECH, INC. |
发明人 |
KOCHAR, MANISH S.;BODNER, ANNE J.;HUFF, JOHN P.;FORD, GLEN M.;STEEL, JAMES S. |
分类号 |
G01N33/543;(IPC1-7):G01N33/543;G01N37/00;G01N15/06;G01N33/546;G01N33/569 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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