发明名称 |
METHOD FOR ENHANCING THE SOLUBILITY OF SUBSTANTIALLY WATER-INSOLUBLE COMPOUNDS |
摘要 |
Methods for enhancing the water-solubility of substantially water-insoluble compounds are disclosed by combining such compounds with a water-soluble polymer, e.g., polyalkylene oxide polymer or a cellulose ether, having a molecular weight of from about 50,000 to 7,000,000 grams/per gram in an amount effective to enhance the water-solubility of the compound in an acidic environment, e.g., pH less than about 5. Compositions comprising the compounds having enhanced water solubility are also disclosed.
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申请公布号 |
CA2247410(A1) |
申请公布日期 |
1998.05.14 |
申请号 |
CA19972247410 |
申请日期 |
1997.10.31 |
申请人 |
UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION |
发明人 |
DONABEDIAN, DAVID H.;CLARKE, EIKE M.A.;MARLIN, LAWRENCE |
分类号 |
A61K31/18;A61K31/19;A61K31/425;A61K31/54;A61K47/34;A61K47/38;(IPC1-7):A61K47/38 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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