发明名称 METHOD FOR ENHANCING THE SOLUBILITY OF SUBSTANTIALLY WATER-INSOLUBLE COMPOUNDS
摘要 Methods for enhancing the water-solubility of substantially water-insoluble compounds are disclosed by combining such compounds with a water-soluble polymer, e.g., polyalkylene oxide polymer or a cellulose ether, having a molecular weight of from about 50,000 to 7,000,000 grams/per gram in an amount effective to enhance the water-solubility of the compound in an acidic environment, e.g., pH less than about 5. Compositions comprising the compounds having enhanced water solubility are also disclosed.
申请公布号 CA2247410(A1) 申请公布日期 1998.05.14
申请号 CA19972247410 申请日期 1997.10.31
申请人 UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 发明人 DONABEDIAN, DAVID H.;CLARKE, EIKE M.A.;MARLIN, LAWRENCE
分类号 A61K31/18;A61K31/19;A61K31/425;A61K31/54;A61K47/34;A61K47/38;(IPC1-7):A61K47/38 主分类号 A61K31/18
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