发明名称 |
METHOD FOR ENHANCING THE SOLUBILITY OF SUBSTANTIALLY WATER-INSOLUBLE COMPOUNDS |
摘要 |
Methods for enhancing the water-solubility of substantially water-insoluble compounds are disclosed by combining such compounds with a water-soluble polymer, e.g., polyalkylene oxide polymer or a cellulose ether, having a molecular weight of from about 50,000 to 7,000,000 grams/per gram in an amount effective to enhance the water-solubility of the compound in an acidic environment, e.g., pH less than about 5. Compositions comprising the compounds having enhanced water solubility are also disclosed. |
申请公布号 |
WO9819708(A2) |
申请公布日期 |
1998.05.14 |
申请号 |
WO1997US19831 |
申请日期 |
1997.10.31 |
申请人 |
UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORP;DONABEDIAN, DAVID, H.;MARLIN, LAWRENCE;CLARK, ELKE, M., A. |
发明人 |
DONABEDIAN, DAVID, H.;MARLIN, LAWRENCE;CLARK, ELKE, M., A. |
分类号 |
A61K9/14;A61K47/10;A61K47/38 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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