MEDICATION INFUSION PUMP WITH PROTEIN STABILIZED SURFACE COATING

摘要

A medication infusion pump is provided for use in the delivery of a selected medication to a patient, wherein the pump includes internal surface coatings defining protein stable surfaces. In accordance with the invention, hydrophilic internal surfaces and related coating methods are provided to reduce or eliminate accumulation of medication deposits which can otherwise occur when handling complex protein-based medication. Preferred hydrophilic pump surfaces include hydrophilic surfactants (PEO) or (PEG) coatings which exhibit very low protein adsorption characteristics. Several methods are disclosed for producing such coatings, including direct surface modification, covalent and noncovalent attachment of polymers, and covalent attachment through a saline primer.