IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS
摘要
<p>A process is disclosed for the preparation of
6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and
4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids:
or</p>
申请公布号
EP0840736(A1)
申请公布日期
1998.05.13
申请号
EP19960918202
申请日期
1996.06.06
申请人
PERSEPTIVE BIOSYSTEMS, INC.
发明人
COULL, JAMES, M.;EGHOLM, MICHAEL;HODGE, RICHARD, P.;ISMAIL, MOHAMED;RAJUR, S., B.
