This invention is directed to L5 shuttle phasmids capable of delivering foreign DNA into mycobacteria and to methods of producing L5 shuttle phasmids. In addition, this invention is directed to a method of generating mycobacterial mutations and to a method of producing mycobacterial vaccines.
申请公布号
US5750384(A)
申请公布日期
1998.05.12
申请号
US19940247901
申请日期
1994.05.23
申请人
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY;UNIVERSITY OF PITTSBURGH
发明人
JACOBS, WILLIAM R.;HATFULL, GRAHAM F.;BARDAROV, STOYAN;MCADAM, RUTH
