发明名称 |
Azepanes and their ring homologues having protein kinase inhibiting activity |
摘要 |
The compounds of formula I <IMAGE> I wherein R1-R9, R15, A, X, Y, Z and n have the meaning given in the specification are active as protein kinase inhibitors and can be used as medicaments, particularly for the treatment of inflammatory skin disorders and alopecia.
|
申请公布号 |
US5750706(A) |
申请公布日期 |
1998.05.12 |
申请号 |
US19960706896 |
申请日期 |
1996.09.03 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
BARBIER, PIERRE;HUBER, ISABELLE;SCHNEIDER, FERNAND;STADLWIESER, JOSEF;TAYLOR, SVEN |
分类号 |
A61K31/00;A61K31/40;A61K31/44;A61K31/4427;A61K31/445;A61K31/4468;A61K31/55;A61P17/00;A61P17/06;A61P29/00;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D207/12;C07D207/14;C07D211/44;C07D211/56;C07D223/08;C07D223/12;C07D401/12;C07D401/14;C07D405/12;C07D417/12;(IPC1-7):C07D207/12 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|