Novel P2Y receptor antagonists derived from ATP and UTP are described. P2Y receptor antagonists with competitive antagonist activity at the P2Y receptor are described in particular, as are P2Y receptor antagonists that bind selectively to the P2Y1 receptor. Also described herein are methods of detecting a P2Y receptor in a biological sample.
申请公布号
WO9818430(A2)
申请公布日期
1998.05.07
申请号
WO1997US19922
申请日期
1997.10.23
申请人
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;BOYER, JOSE, L.;HARDEN, T., KENDALL;JACOBSON, KENNETH, A.;CAMAIONI, EMIDIO