发明名称 |
ANTI-P53 SINGLE-CHAIN ANTIBODY FRAGMENTS AND THEIR USES |
摘要 |
The invention concerns single-chain antibodies directed against the p53 protein, capable of being expressed in tumoral cells, capable of restoring a DNA binding in vitro and a transcription activator function in vivo. The invention also concerns nucleic acids coding for these molecules, the vectors containing them and their uses.
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申请公布号 |
WO9818825(A1) |
申请公布日期 |
1998.05.07 |
申请号 |
WO1997FR01921 |
申请日期 |
1997.10.27 |
申请人 |
RHONE-POULENC RORER S.A.;BRACCO, LAURENT;DEBUSSCHE, LAURENT |
发明人 |
BRACCO, LAURENT;DEBUSSCHE, LAURENT |
分类号 |
C12N15/09;A61K31/711;A61K35/00;A61K38/00;A61K39/395;A61K48/00;C07K14/47;C07K16/18;C12P21/08;(IPC1-7):C07K16/18;C12N15/13 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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